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Systematic identification of phenotypically enriched loci using a patient network of genomic disorders

BACKGROUND: Network medicine is a promising new discipline that combines systems biology approaches and network science to understand the complexity of pathological phenotypes. Given the growing availability of personalized genomic and phenotypic profiles, network models offer a robust integrative f...

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Detalles Bibliográficos
Autores principales: Reyes-Palomares, Armando, Bueno, Aníbal, Rodríguez-López, Rocío, Medina, Miguel Ángel, Sánchez-Jiménez, Francisca, Corpas, Manuel, Ranea, Juan A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792099/
https://www.ncbi.nlm.nih.gov/pubmed/26980139
http://dx.doi.org/10.1186/s12864-016-2569-6