Deletion of endogenous Tau proteins is not detrimental in Drosophila

Human Tau (hTau) is a highly soluble and natively unfolded protein that binds to microtubules within neurons. Its dysfunction and aggregation into insoluble paired helical filaments is involved in the pathogenesis of Alzheimer’s disease (AD), constituting, together with accumulated β-amyloid (Aβ) pe...

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Detalles Bibliográficos
Autores principales: Burnouf, Sylvie, Grönke, Sebastian, Augustin, Hrvoje, Dols, Jacqueline, Gorsky, Marianna Karina, Werner, Jennifer, Kerr, Fiona, Alic, Nazif, Martinez, Pedro, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792132/
https://www.ncbi.nlm.nih.gov/pubmed/26976084
http://dx.doi.org/10.1038/srep23102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792132/
https://www.ncbi.nlm.nih.gov/pubmed/26976084
http://dx.doi.org/10.1038/srep23102

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