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A generic screening platform for inhibitors of virus induced cell fusion using cellular electrical impedance

Fusion of the viral envelope with host cell membranes is an essential step in the life cycle of all enveloped viruses. Despite such a clear target for antiviral drug development, few anti-fusion drugs have progressed to market. One significant hurdle is the absence of a generic, high-throughput, rep...

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Detalles Bibliográficos
Autores principales: Watterson, Daniel, Robinson, Jodie, Chappell, Keith J., Butler, Mark S., Edwards, David J., Fry, Scott R., Bermingham, Imogen M., Cooper, Matthew A., Young, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792136/
https://www.ncbi.nlm.nih.gov/pubmed/26976324
http://dx.doi.org/10.1038/srep22791