Cargando…
Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer
Gene therapy for cystic fibrosis using non-viral, plasmid-based formulations has been the subject of intensive research for over two decades but a clinically viable product has yet to materialise in large part due to inefficient transgene expression. Minicircle DNA give enhanced and more persistent...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792149/ https://www.ncbi.nlm.nih.gov/pubmed/26975732 http://dx.doi.org/10.1038/srep23125 |