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Oxidative stress generated during monensin treatment contributes to altered Toxoplasma gondii mitochondrial function

The ionophore monensin displays potent activities against several coccidian parasites of veterinary and medical importance including the opportunistic pathogen of humans, Toxoplasma gondii. While monensin is used widely in animals, toxicity impedes its use in humans. Nonetheless, given its potency,...

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Detalles Bibliográficos
Autores principales: Charvat, Robert A., Arrizabalaga, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792157/
https://www.ncbi.nlm.nih.gov/pubmed/26976749
http://dx.doi.org/10.1038/srep22997