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Inhibiting microRNA-449 Attenuates Cisplatin-Induced Injury in NRK-52E Cells Possibly via Regulating the SIRT1/P53/BAX Pathway

BACKGROUND: Acute kidney injury (AKI) is quite common in the patients who frequently use the anticancer drug cisplatin. microRNAs (miRNAs) are powerful tools in modulating the expression of key factors in disease progression, but little is known about roles of miRNAs in AKI. This study explored the...

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Detalles Bibliográficos
Autores principales: Qin, Wen, Xie, Wei, Yang, Xi, Xia, Ning, Yang, Kunling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792225/
https://www.ncbi.nlm.nih.gov/pubmed/26968221
http://dx.doi.org/10.12659/MSM.897187