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PE_PGRS33 Contributes to Mycobacterium tuberculosis Entry in Macrophages through Interaction with TLR2

PE_PGRS represent a large family of proteins typical of pathogenic mycobacteria whose members are characterized by an N-terminal PE domain followed by a large Gly-Ala repeat-rich C-terminal domain. Despite the abundance of PE_PGRS-coding genes in the Mycobacterium tuberculosis (Mtb) genome their rol...

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Detalles Bibliográficos
Autores principales: Palucci, Ivana, Camassa, Serena, Cascioferro, Alessandro, Sali, Michela, Anoosheh, Saber, Zumbo, Antonella, Minerva, Mariachiara, Iantomasi, Raffaella, De Maio, Flavio, Di Sante, Gabriele, Ria, Francesco, Sanguinetti, Maurizio, Palù, Giorgio, Brennan, Michael J., Manganelli, Riccardo, Delogu, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792380/
https://www.ncbi.nlm.nih.gov/pubmed/26978522
http://dx.doi.org/10.1371/journal.pone.0150800