Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

The mitochondrial (mt) genome is present in many copies in human cells, and intra-individual variation in mtDNA sequences is known as heteroplasmy. Recent studies found that heteroplasmies are highly tissue-specific, site-specific, and allele-specific, however the functional implications have not be...

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Detalles Bibliográficos
Autores principales: Wachsmuth, Manja, Hübner, Alexander, Li, Mingkun, Madea, Burkhard, Stoneking, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792396/
https://www.ncbi.nlm.nih.gov/pubmed/26978189
http://dx.doi.org/10.1371/journal.pgen.1005939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792396/
https://www.ncbi.nlm.nih.gov/pubmed/26978189
http://dx.doi.org/10.1371/journal.pgen.1005939

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