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High Frequency Hearing Loss and Hyperactivity in DUX4 Transgenic Mice

Facioscapulohumeral muscular dystrophy (FSHD) is caused by mutations leading to ectopic expression of the transcription factor DUX4, and encompasses both muscle-related and non-muscle phenotypes. Mouse models bearing this gene represent valuable tools to investigate which pathologies are due to DUX4...

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Detalles Bibliográficos
Autores principales: Dandapat, Abhijit, Perrin, Benjamin J., Cabelka, Christine, Razzoli, Maria, Ervasti, James M., Bartolomucci, Alessandro, Lowe, Dawn A., Kyba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792399/
https://www.ncbi.nlm.nih.gov/pubmed/26978271
http://dx.doi.org/10.1371/journal.pone.0151467