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Assessing the Relationship between Lung Density and Function with Oxygen-Enhanced Magnetic Resonance Imaging in a Mouse Model of Emphysema

PURPOSE: A magnetic resonance imaging method is presented that allows for the simultaneous assessment of oxygen delivery, oxygen uptake, and parenchymal density. The technique is applied to a mouse model of porcine pancreatic elastase (PPE) induced lung emphysema in order to investigate how structur...

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Detalles Bibliográficos
Autores principales: Zurek, Magdalena, Sladen, Louise, Johansson, Edvin, Olsson, Marita, Jackson, Sonya, Zhang, Hui, Mayer, Gaell, Hockings, Paul D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792441/
https://www.ncbi.nlm.nih.gov/pubmed/26977928
http://dx.doi.org/10.1371/journal.pone.0151211