Fibronectin Modulates Cell Adhesion and Signaling to Promote Single Cell Migration of Highly Invasive Oral Squamous Cell Carcinoma

Cell migration is regulated by adhesion to the extracellular matrix (ECM) through integrins and activation of small RhoGTPases, such as RhoA and Rac1, resulting in changes to actomyosin organization. During invasion, epithelial-derived tumor cells switch from laminin-enriched basal membrane to colla...

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Detalles Bibliográficos
Autores principales: Ramos, Grasieli de Oliveira, Bernardi, Lisiane, Lauxen, Isabel, Sant’Ana Filho, Manoel, Horwitz, Alan Rick, Lamers, Marcelo Lazzaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792484/
https://www.ncbi.nlm.nih.gov/pubmed/26978651
http://dx.doi.org/10.1371/journal.pone.0151338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792484/
https://www.ncbi.nlm.nih.gov/pubmed/26978651
http://dx.doi.org/10.1371/journal.pone.0151338

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