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Renal effects of BRAF inhibitors: a systematic review by the Cancer and the Kidney International Network

Advanced melanoma has been traditionally unresponsive to standard chemotherapy agents and used to have a dismal prognosis. Genetically targeted small-molecule inhibitors of the oncogenic BRAF V600 mutation or a downstream signaling partner (MEK mitogen-activated protein kinase) are effective treatme...

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Detalles Bibliográficos
Autores principales: Wanchoo, Rimda, Jhaveri, Kenar D., Deray, Gilbert, Launay-Vacher, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792624/
https://www.ncbi.nlm.nih.gov/pubmed/26985376
http://dx.doi.org/10.1093/ckj/sfv149