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Design and synthesis of some substituted thiazolo[3,2-a]pyrimidine derivatives of potential biological activities

In continuation to our previous work, thiazolopyrimidines 2a–x were synthesized through intramolecular cyclization of 2-phenacylthio-dihydropyrimidine hydrobromides 1a–x using polyphosphoric acid. On the other hand, thiazolo[3,2-a]pyrimidine-3-one 3 was coupled with aryldiazonium salts or condensed...

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Detalles Bibliográficos
Autores principales: Abdel Moty, Samia G., Hussein, Mostafa A., Abdel Aziz, Salah A., Abou-Salim, Mahrous A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792894/
https://www.ncbi.nlm.nih.gov/pubmed/27013904
http://dx.doi.org/10.1016/j.jsps.2013.12.016