Remote loading of doxorubicin into liposomes by transmembrane pH gradient to reduce toxicity toward H9c2 cells

The use of doxorubicin (DOX) is limited by its dose-dependent cardiotoxicity. Entrapped DOX in liposome has been shown to reduce cardiotoxicity. Results showed that about 92% of the total drug was encapsulated in liposome. The release experiments showed a weak DOX leakage in both culture medium and...

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Detalles Bibliográficos
Autores principales: Alyane, Mohamed, Barratt, Gillian, Lahouel, Mesbah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792903/
https://www.ncbi.nlm.nih.gov/pubmed/27013909
http://dx.doi.org/10.1016/j.jsps.2015.02.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792903/
https://www.ncbi.nlm.nih.gov/pubmed/27013909
http://dx.doi.org/10.1016/j.jsps.2015.02.014

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