Alignment independent 3D-QSAR, quantum calculations and molecular docking of Mer specific tyrosine kinase inhibitors as anticancer drugs

Mer receptor tyrosine kinase is a promising novel cancer therapeutic target in many human cancers, because abnormal activation of Mer has been implicated in survival signaling and chemoresistance. 3D-QSAR analyses based on alignment independent descriptors were performed on a series of 81 Mer specif...

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Detalles Bibliográficos
Autores principales: Shiri, Fereshteh, Pirhadi, Somayeh, Ghasemi, Jahan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792907/
https://www.ncbi.nlm.nih.gov/pubmed/27013913
http://dx.doi.org/10.1016/j.jsps.2015.03.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792907/
https://www.ncbi.nlm.nih.gov/pubmed/27013913
http://dx.doi.org/10.1016/j.jsps.2015.03.012

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