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Constructing 3D interaction maps from 1D epigenomes

The human genome is tightly packaged into chromatin whose functional output depends on both one-dimensional (1D) local chromatin states and three-dimensional (3D) genome organization. Currently, chromatin modifications and 3D genome organization are measured by distinct assays. An emerging question...

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Detalles Bibliográficos
Autores principales: Zhu, Yun, Chen, Zhao, Zhang, Kai, Wang, Mengchi, Medovoy, David, Whitaker, John W., Ding, Bo, Li, Nan, Zheng, Lina, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792925/
https://www.ncbi.nlm.nih.gov/pubmed/26960733
http://dx.doi.org/10.1038/ncomms10812