Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation

Tyrosine (Y)-recombinases have evolved to deliver mechanistically different reactions on a variety of substrates, but these evolutionary transitions are poorly understood. Among them, integron integrases are hybrid systems recombining single- and double-stranded DNA partners. These reactions are asy...

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Detalles Bibliográficos
Autores principales: Escudero, Jose Antonio, Loot, Celine, Parissi, Vincent, Nivina, Aleksandra, Bouchier, Christiane, Mazel, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792948/
https://www.ncbi.nlm.nih.gov/pubmed/26961432
http://dx.doi.org/10.1038/ncomms10937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792948/
https://www.ncbi.nlm.nih.gov/pubmed/26961432
http://dx.doi.org/10.1038/ncomms10937

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