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Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation
Tyrosine (Y)-recombinases have evolved to deliver mechanistically different reactions on a variety of substrates, but these evolutionary transitions are poorly understood. Among them, integron integrases are hybrid systems recombining single- and double-stranded DNA partners. These reactions are asy...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792948/ https://www.ncbi.nlm.nih.gov/pubmed/26961432 http://dx.doi.org/10.1038/ncomms10937 |