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Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

The biosynthesis of phospholipids and glycolipids are critical pathways for virtually all cell membranes. PatA is an essential membrane associated acyltransferase involved in the biosynthesis of mycobacterial phosphatidyl-myo-inositol mannosides (PIMs). The enzyme transfers a palmitoyl moiety from p...

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Detalles Bibliográficos
Autores principales: Albesa-Jové, David, Svetlíková, Zuzana, Tersa, Montse, Sancho-Vaello, Enea, Carreras-González, Ana, Bonnet, Pascal, Arrasate, Pedro, Eguskiza, Ander, Angala, Shiva K., Cifuente, Javier O., Korduláková, Jana, Jackson, Mary, Mikušová, Katarína, Guerin, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792965/
https://www.ncbi.nlm.nih.gov/pubmed/26965057
http://dx.doi.org/10.1038/ncomms10906