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Simeprevir and Sofosbuvir Combination Treatment in a Patient with HCV Cirrhosis and HbS Beta 0-Thalassemia: Efficacy and Safety despite Baseline Hyperbilirubinemia

Hyperbilirubinemia is an adverse reaction of simeprevir (SMV). The majority of these patients were taking concurrent ribavirin presenting elevated unconjugated hyperbilirubinemia due to hemolysis. However, cases of hepatic failure with elevated bilirubin level have also been reported in patients wit...

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Detalles Bibliográficos
Autores principales: Papadopoulos, Nikolaos, Deutsch, Melanie, Georgalas, Athanasios, Poulakidas, Helias, Karnesis, Lazaros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793097/
https://www.ncbi.nlm.nih.gov/pubmed/27042368
http://dx.doi.org/10.1155/2016/7635128