Unique AGG Interruption in the CGG Repeats of the FMR1 Gene Exclusively Found in Asians Linked to a Specific SNP Haplotype

Fragile X syndrome (FXS) is the most common inherited intellectual disability. It is caused by the occurrence of more than 200 pure CGG repeats in the FMR1 gene. Normal individuals have 6–54 CGG repeats with two or more stabilizing AGG interruptions occurring once every 9- or 10-CGG-repeat blocks in...

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Detalles Bibliográficos
Autores principales: Limprasert, Pornprot, Thanakitgosate, Janpen, Jaruthamsophon, Kanoot, Sripo, Thanya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793144/
https://www.ncbi.nlm.nih.gov/pubmed/27042357
http://dx.doi.org/10.1155/2016/8319287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793144/
https://www.ncbi.nlm.nih.gov/pubmed/27042357
http://dx.doi.org/10.1155/2016/8319287

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