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The Rtr1p CTD phosphatase autoregulates its mRNA through a degradation pathway involving the REX exonucleases

Rtr1p is a phosphatase that impacts gene expression by modulating the phosphorylation status of the C-terminal domain of the large subunit of RNA polymerase II. Here, we show that Rtr1p is a component of a novel mRNA degradation pathway that promotes its autoregulation through turnover of its own mR...

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Detalles Bibliográficos
Autores principales: Hodko, Domagoj, Ward, Taylor, Chanfreau, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793211/
https://www.ncbi.nlm.nih.gov/pubmed/26843527
http://dx.doi.org/10.1261/rna.055723.115