Cargando…
The Rtr1p CTD phosphatase autoregulates its mRNA through a degradation pathway involving the REX exonucleases
Rtr1p is a phosphatase that impacts gene expression by modulating the phosphorylation status of the C-terminal domain of the large subunit of RNA polymerase II. Here, we show that Rtr1p is a component of a novel mRNA degradation pathway that promotes its autoregulation through turnover of its own mR...
Autores principales: | Hodko, Domagoj, Ward, Taylor, Chanfreau, Guillaume |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793211/ https://www.ncbi.nlm.nih.gov/pubmed/26843527 http://dx.doi.org/10.1261/rna.055723.115 |
Ejemplares similares
-
RNA Polymerase II CTD phosphatase Rtr1 fine-tunes transcription termination
por: Victorino, Jose F., et al.
Publicado: (2020) -
The Association of Rpb4 with RNA Polymerase II Depends on CTD Ser5P Phosphatase Rtr1 and Influences mRNA Decay in Saccharomyces cerevisiae
por: Garrido-Godino, Ana I., et al.
Publicado: (2022) -
The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity
por: Xiang, Kehui, et al.
Publicado: (2012) -
Splicing-Mediated Autoregulation Modulates Rpl22p Expression in Saccharomyces cerevisiae
por: Gabunilas, Jason, et al.
Publicado: (2016) -
Validität und Reliabilität virtualisierter RTR-Messungen
por: Waldvogel, Thomas, et al.
Publicado: (2021)