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The in vivo dynamics of TCERG1, a factor that couples transcriptional elongation with splicing

Coupling between transcription and RNA processing is key for gene regulation. Using live-cell photobleaching techniques, we investigated the factor TCERG1, which coordinates transcriptional elongation with splicing. We demonstrate that TCERG1 is highly mobile in the nucleoplasm and that this mobilit...

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Detalles Bibliográficos
Autores principales: Sánchez-Hernández, Noemí, Boireau, Stéphanie, Schmidt, Ute, Muñoz-Cobo, Juan Pablo, Hernández-Munain, Cristina, Bertrand, Edouard, Suñé, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793212/
https://www.ncbi.nlm.nih.gov/pubmed/26873599
http://dx.doi.org/10.1261/rna.052795.115