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Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis

The RNA exosome is essential for 3′ processing of functional RNA species and degradation of aberrant RNAs in eukaryotic cells. Recent reports have defined the substrates of the exosome catalytic domains and solved the multimeric structure of the exosome complex. However, regulation of exosome activi...

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Detalles Bibliográficos
Autores principales: Knight, John R.P., Bastide, Amandine, Peretti, Diego, Roobol, Anne, Roobol, Jo, Mallucci, Giovanna R., Smales, C. Mark, Willis, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793216/
https://www.ncbi.nlm.nih.gov/pubmed/26857222
http://dx.doi.org/10.1261/rna.054411.115