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Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis
The RNA exosome is essential for 3′ processing of functional RNA species and degradation of aberrant RNAs in eukaryotic cells. Recent reports have defined the substrates of the exosome catalytic domains and solved the multimeric structure of the exosome complex. However, regulation of exosome activi...
Autores principales: | Knight, John R.P., Bastide, Amandine, Peretti, Diego, Roobol, Anne, Roobol, Jo, Mallucci, Giovanna R., Smales, C. Mark, Willis, Anne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793216/ https://www.ncbi.nlm.nih.gov/pubmed/26857222 http://dx.doi.org/10.1261/rna.054411.115 |
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