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Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

BACKGROUND: Extracellular vesicles (EVs) are attractive candidate drug delivery systems due to their ability to functionally transport biological cargo to recipient cells. However, the apparent lack of target cell specificity of exogenously administered EVs limits their therapeutic applicability. In...

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Detalles Bibliográficos
Autores principales: Kooijmans, Sander A. A., Aleza, Clara Gómez, Roffler, Steve R., van Solinge, Wouter W., Vader, Pieter, Schiffelers, Raymond M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793259/
https://www.ncbi.nlm.nih.gov/pubmed/26979463
http://dx.doi.org/10.3402/jev.v5.31053