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Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting
BACKGROUND: Extracellular vesicles (EVs) are attractive candidate drug delivery systems due to their ability to functionally transport biological cargo to recipient cells. However, the apparent lack of target cell specificity of exogenously administered EVs limits their therapeutic applicability. In...
Autores principales: | Kooijmans, Sander A. A., Aleza, Clara Gómez, Roffler, Steve R., van Solinge, Wouter W., Vader, Pieter, Schiffelers, Raymond M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Co-Action Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793259/ https://www.ncbi.nlm.nih.gov/pubmed/26979463 http://dx.doi.org/10.3402/jev.v5.31053 |
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