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Analysis of the mechanical properties of wild type and hyperstable mutants of the HIV-1 capsid

BACKGROUND: The human immunodeficiency virus (HIV-1) capsid is a self-assembled protein shell that contains the viral genome. During the stages between viral entry into a host cell and nuclear import of the viral DNA, the capsid dissociates in a process known as uncoating, which leads to the release...

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Detalles Bibliográficos
Autores principales: Ramalho, Ruben, Rankovic, Sanela, Zhou, Jing, Aiken, Christopher, Rousso, Itay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793510/
https://www.ncbi.nlm.nih.gov/pubmed/26979152
http://dx.doi.org/10.1186/s12977-016-0250-4