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Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcoma
BACKGROUND: Matrix metalloproteinases (MMPs) are crucially involved in the regulation of multiple stages of cancer progression. Elevated MMP levels have been associated with the development of metastases and poor prognosis in several types of cancer. However, the role of MMPs in osteosarcoma and the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793522/ https://www.ncbi.nlm.nih.gov/pubmed/26979530 http://dx.doi.org/10.1186/s12885-016-2266-5 |