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Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcoma

BACKGROUND: Matrix metalloproteinases (MMPs) are crucially involved in the regulation of multiple stages of cancer progression. Elevated MMP levels have been associated with the development of metastases and poor prognosis in several types of cancer. However, the role of MMPs in osteosarcoma and the...

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Detalles Bibliográficos
Autores principales:	Kunz, Pierre, Sähr, Heiner, Lehner, Burkhard, Fischer, Christian, Seebach, Elisabeth, Fellenberg, Jörg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793522/ https://www.ncbi.nlm.nih.gov/pubmed/26979530 http://dx.doi.org/10.1186/s12885-016-2266-5

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