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Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis

Human T cell leukemia virus type 1 (HTLV-1) is an oncogenic retrovirus responsible for the development of adult T-cell leukemia (ATL). Although HTLV-1 harbors an oncogene, tax, that transforms T cells in vitro and induces leukemia in transgenic mice, tax expression is frequently disrupted in ATL, ma...

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Detalles Bibliográficos
Autores principales: Ma, Guangyong, Yasunaga, Jun-ichirou, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793531/
https://www.ncbi.nlm.nih.gov/pubmed/26979059
http://dx.doi.org/10.1186/s12977-016-0249-x