Type I interferon inhibits varicella-zoster virus replication by interfering with the dynamic interaction between mediator and IE62 within replication compartments

BACKGROUND: Varicella-zoster virus (VZV) is the causative agent of varicella and zoster. The immediate-early protein, IE62 is the predominant VZ virion tegument protein, transactivating the expression of all kinetic classes of VZV genes. IE62 is localized to punctae that form DNA replication compart...

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Detalles Bibliográficos
Autores principales: Ku, Chia-Chi, Chang, Yi-Hsuan, Chien, Yun, Lee, Tsung-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793741/
https://www.ncbi.nlm.nih.gov/pubmed/26985360
http://dx.doi.org/10.1186/s13578-016-0086-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793741/
https://www.ncbi.nlm.nih.gov/pubmed/26985360
http://dx.doi.org/10.1186/s13578-016-0086-6

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