Type I interferon inhibits varicella-zoster virus replication by interfering with the dynamic interaction between mediator and IE62 within replication compartments

BACKGROUND: Varicella-zoster virus (VZV) is the causative agent of varicella and zoster. The immediate-early protein, IE62 is the predominant VZ virion tegument protein, transactivating the expression of all kinetic classes of VZV genes. IE62 is localized to punctae that form DNA replication compart...

Descripción completa

Detalles Bibliográficos
Autores principales: Ku, Chia-Chi, Chang, Yi-Hsuan, Chien, Yun, Lee, Tsung-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793741/
https://www.ncbi.nlm.nih.gov/pubmed/26985360
http://dx.doi.org/10.1186/s13578-016-0086-6

Ejemplares similares

Ejemplares similares