Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma

To investigate the underlying causes of chemoresistance in malignant pleural mesothelioma, we have studied mesothelioma cell lines as 3D spheroids, which acquire increased chemoresistance compared to 2D monolayers. We asked whether the gene expression of 3D spheroids would reveal mechanisms of resis...

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Detalles Bibliográficos
Autores principales: Barbone, Dario, Van Dam, Loes, Follo, Carlo, Jithesh, Puthen V., Zhang, Shu-Dong, Richards, William G., Bueno, Raphael, Fennell, Dean A., Broaddus, V. Courtney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794185/
https://www.ncbi.nlm.nih.gov/pubmed/26982031
http://dx.doi.org/10.1371/journal.pone.0150044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794185/
https://www.ncbi.nlm.nih.gov/pubmed/26982031
http://dx.doi.org/10.1371/journal.pone.0150044

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