ENTPRISE: An Algorithm for Predicting Human Disease-Associated Amino Acid Substitutions from Sequence Entropy and Predicted Protein Structures

The advance of next-generation sequencing technologies has made exome sequencing rapid and relatively inexpensive. A major application of exome sequencing is the identification of genetic variations likely to cause Mendelian diseases. This requires processing large amounts of sequence information an...

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Detalles Bibliográficos
Autores principales: Zhou, Hongyi, Gao, Mu, Skolnick, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794227/
https://www.ncbi.nlm.nih.gov/pubmed/26982818
http://dx.doi.org/10.1371/journal.pone.0150965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794227/
https://www.ncbi.nlm.nih.gov/pubmed/26982818
http://dx.doi.org/10.1371/journal.pone.0150965

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