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Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection

HIV targets the gut mucosa early in infection, causing immune and epithelial barrier dysfunction and disease progression. However, gut mucosal sensing and innate immune signaling through mucosal pattern recognition receptors (PRR) during HIV infection and disease progression are not well defined. Us...

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Detalles Bibliográficos
Autores principales: Glavan, Tiffany W., Gaulke, Christopher A, Rocha, Clarissa Santos, Sankaran-Walters, Sumathi, Hirao, Lauren A, Raffatellu, Manuela, Jiang, Guochun, Bäumler, Andreas J., Goulart, Luiz R., Dandekar, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794436/
https://www.ncbi.nlm.nih.gov/pubmed/26376368
http://dx.doi.org/10.1038/mi.2015.92