Cargando…
Cutaneous Side Effects of BRAF Inhibitors in Advanced Melanoma: Review of the Literature
The incidence of melanoma has recently been increasing. BRAF mutations have been found in 40–60% of melanomas. The increased activity of BRAF V600E leads to the activation of downstream signaling through the mitogen-activated protein kinase (MAPK) pathway, which plays a key role as a regulator of ce...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794559/ https://www.ncbi.nlm.nih.gov/pubmed/27042173 http://dx.doi.org/10.1155/2016/5361569 |