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Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers

Immobilization of nucleic acid aptamer recognition elements selected free in solution onto the surface of biosensor platforms has proven challenging. This study investigated the binding of multiple aptamer/target pairs immobilized on a commercially available microarray as a model system mimicking bi...

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Detalles Bibliográficos
Autores principales: Martin, Jennifer A., Chushak, Yaroslav, Chávez, Jorge L., Hagen, Joshua A., Kelley-Loughnane, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794571/
https://www.ncbi.nlm.nih.gov/pubmed/27042344
http://dx.doi.org/10.1155/2016/9718612