Improved Stability of a Model IgG3 by DoE-Based Evaluation of Buffer Formulations

Formulating appropriate storage conditions for biopharmaceutical proteins is essential for ensuring their stability and thereby their purity, potency, and safety over their shelf-life. Using a model murine IgG3 produced in a bioreactor system, multiple formulation compositions were systematically ex...

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Detalles Bibliográficos
Autores principales: Chavez, Brittany K., Agarabi, Cyrus D., Read, Erik K., Boyne II, Michael T., Khan, Mansoor A., Brorson, Kurt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794585/
https://www.ncbi.nlm.nih.gov/pubmed/27042659
http://dx.doi.org/10.1155/2016/2074149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794585/
https://www.ncbi.nlm.nih.gov/pubmed/27042659
http://dx.doi.org/10.1155/2016/2074149

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