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Improved Stability of a Model IgG3 by DoE-Based Evaluation of Buffer Formulations
Formulating appropriate storage conditions for biopharmaceutical proteins is essential for ensuring their stability and thereby their purity, potency, and safety over their shelf-life. Using a model murine IgG3 produced in a bioreactor system, multiple formulation compositions were systematically ex...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794585/ https://www.ncbi.nlm.nih.gov/pubmed/27042659 http://dx.doi.org/10.1155/2016/2074149 |