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Micheliolide inhibits LPS-induced inflammatory response and protects mice from LPS challenge

Sepsis is the principal cause of fatality in the intensive care units worldwide. It involves uncontrolled inflammatory response resulting in multi-organ failure and even death. Micheliolide (MCL), a sesquiterpene lactone, was reported to inhibit dextran sodium sulphate (DSS)-induced inflammatory int...

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Detalles Bibliográficos
Autores principales: Qin, Xiangyang, Jiang, Xinru, Jiang, Xin, Wang, Yuli, Miao, Zhulei, He, Weigang, Yang, Guizhen, Lv, Zhenhui, Yu, Yizhi, Zheng, Yuejuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794649/
https://www.ncbi.nlm.nih.gov/pubmed/26984741
http://dx.doi.org/10.1038/srep23240