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Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA

The cell adhesion protein and tumour suppressor E-cadherin exhibits important functions in the prevention of gastric cancer. As a class-I carcinogen, Helicobacter pylori (H. pylori) has developed a unique strategy to interfere with E-cadherin functions. In previous studies, we have demonstrated that...

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Detalles Bibliográficos
Autores principales: Schmidt, Thomas P., Perna, Anna M., Fugmann, Tim, Böhm, Manja, Jan Hiss, Haller, Sarah, Götz, Camilla, Tegtmeyer, Nicole, Hoy, Benjamin, Rau, Tilman T., Neri, Dario, Backert, Steffen, Schneider, Gisbert, Wessler, Silja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794652/
https://www.ncbi.nlm.nih.gov/pubmed/26983597
http://dx.doi.org/10.1038/srep23264