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A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance

Despite significant advances in the treatment of hepatitis C virus (HCV) infection, the need to develop preventative vaccines remains. Identification of the best vaccine candidates and evaluation of their performance in preclinical and clinical development will require appropriate neutralization ass...

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Detalles Bibliográficos
Autores principales: Urbanowicz, Richard A., McClure, C. Patrick, Brown, Richard J. P., Tsoleridis, Theocharis, Persson, Mats A. A., Krey, Thomas, Irving, William L., Ball, Jonathan K., Tarr, Alexander W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794667/
https://www.ncbi.nlm.nih.gov/pubmed/26699643
http://dx.doi.org/10.1128/JVI.02700-15