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The CagA toxin of Helicobacter pylori: abundant production but relatively low amount translocated

CagA is one of the most studied pathogenicity factors of the bacterial pathogen Helicobacter pylori. It is injected into host cells via the H. pylori cag-Type IV secretion system. Due to its association with gastric cancer, CagA is classified as oncogenic protein. At the same time CagA represents th...

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Detalles Bibliográficos
Autores principales: Jiménez-Soto, Luisa F., Haas, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794710/
https://www.ncbi.nlm.nih.gov/pubmed/26983895
http://dx.doi.org/10.1038/srep23227