SIK2 regulates fasting-induced PPARα activity and ketogenesis through p300

Fatty acid oxidation and subsequent ketogenesis is one of the major mechanisms to maintain hepatic lipid homeostasis under fasting conditions. Fasting hormone glucagon has been shown to stimulate ketone body production through activation of PPARα; however, the signal pathway linking glucagon to PPAR...

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Detalles Bibliográficos
Autores principales: Zhang, Zhen-Ning, Gong, Lulu, Lv, Sihan, Li, Jian, Tai, Xiaolu, Cao, Wenqi, Peng, Bing, Qu, Shen, Li, Weida, Zhang, Chao, Luan, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794759/
https://www.ncbi.nlm.nih.gov/pubmed/26983400
http://dx.doi.org/10.1038/srep23317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794759/
https://www.ncbi.nlm.nih.gov/pubmed/26983400
http://dx.doi.org/10.1038/srep23317

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