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The 2.2‐Angstrom resolution crystal structure of the carboxy‐terminal region of ataxin‐3

An expansion of polyglutamine (polyQ) sequence in ataxin‐3 protein causes spinocerebellar ataxia type 3, an inherited neurodegenerative disorder. The crystal structure of the polyQ‐containing carboxy‐terminal fragment of human ataxin‐3 was solved at 2.2‐Å resolution. The Atxn3 carboxy‐terminal fragm...

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Detalles Bibliográficos
Autores principales: Zhemkov, Vladimir A., Kulminskaya, Anna A., Bezprozvanny, Ilya B., Kim, Meewhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794786/
https://www.ncbi.nlm.nih.gov/pubmed/27047745
http://dx.doi.org/10.1002/2211-5463.12029