Functionally different α-synuclein inclusions yield insight into Parkinson’s disease pathology

The formation of α-synuclein (α-S) amyloid aggregates, called Lewy bodies (LBs), is a hallmark of Parkinson’s disease (PD). The function of LBs in the disease process is however still unclear; they have been associated with both neuroprotection and toxicity. To obtain insight into this contradiction...

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Detalles Bibliográficos
Autores principales: Raiss, Christian C., Braun, Theresa S., Konings, Irene B. M., Grabmayr, Heinrich, Hassink, Gerco C., Sidhu, Arshdeep, le Feber, Joost, Bausch, Andreas R., Jansen, Casper, Subramaniam, Vinod, Claessens, Mireille M. A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794800/
https://www.ncbi.nlm.nih.gov/pubmed/26984067
http://dx.doi.org/10.1038/srep23116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794800/
https://www.ncbi.nlm.nih.gov/pubmed/26984067
http://dx.doi.org/10.1038/srep23116

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