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Epigenetic silencing of miR-181c by DNA methylation in glioblastoma cell lines
BACKGROUND: Post-transcriptional regulation by microRNAs is recognized as one of the major pathways for the control of cellular homeostasis. Less well understood is the transcriptional and epigenetic regulation of genes encoding microRNAs. In the present study we addressed the epigenetic regulation...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794844/ https://www.ncbi.nlm.nih.gov/pubmed/26983574 http://dx.doi.org/10.1186/s12885-016-2273-6 |