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Dramatic response to alectinib in a patient of ALK-rearranged lung cancer with poor performance status

BACKGROUND: Lung cancers with anaplastic lymphoma kinase rearrangements are highly sensitive to anaplastic lymphoma kinase tyrosine kinase inhibition, underscoring the notion that such cancers are addicted to anaplastic lymphoma kinase activity. Several anaplastic lymphoma kinase inhibitors have bee...

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Detalles Bibliográficos
Autores principales: Tanaka, Hisashi, Taima, Kageaki, Morimoto, Takeshi, Nakamura, Kunihiko, Tanaka, Yoshihito, Itoga, Masamichi, Takanashi, Shingo, Okumura, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794901/
https://www.ncbi.nlm.nih.gov/pubmed/26987388
http://dx.doi.org/10.1186/s13104-016-1983-9